The next EPA SBIR Phase I solicitation is scheduled to open in October 2015.

The Biomedical Technologies subtopics aim to support the early stage development of novel products, processes, or services that will enable the delivery of high-quality, economically-efficient healthcare in the U.S. as well as globally.

The Smart Health subtopics aim to support the early stage development of novel devices, components, systems, algorithms, networks, applications, or services that will enable the much needed transformation of healthcare from reactive, hospital-centered, and indemnity-based to proactive, person-centered, preventive, and cost-efficient.

Agricultural and Food Safety Biotechnology, Biosensors, Life Sciences Research Tools, Bioinstrumentation, Synthetic Biology and Metabolic Engineering, Fermentation and Cell Culture Technologies, Computational Biology and Bioinformatics, Advanced Biomanufacturing, Advanced Technologies for Functional Genomics in Organismal Systems

The Chemical and Environmental Technologies (CT) topic covers a wide range of technology areas of current and emerging commercial significance pertaining to the broad chemical industry, the environment and related industrial sectors.

The Advanced Materials and Instrumentation (MI) topic addresses the development of new and improved materials and instruments for a wide variety of commercial and industrial applications. Proposals in Advanced Materials may focus on the creation of innovative material systems and/or on critical fabrication, processing, or manufacturing challenges involved in the successful commercialization of materials. Proposals in Instrumentation may focus on new instruments for use in scientific, industrial, engineering, or manufacturing environments, among others. Types of instruments that will be considered include systems and tools designed for the purposes of detection, characterization, measurement, processing, control, and/or monitoring. A wide variety of applications areas will be considered as part of this topic.

The Nanotechnology subtopic addresses the creation and manipulation of functional materials, devices, and systems with novel properties and functions that are achieved through the control of matter at a submicroscopic scale (from a fraction of nanometer to about 100 nanometers). Proposals should be driven by market needs and demand and should identify both the end users of the proposed technology and the pathway to commercialization.

The Advanced Manufacturing (MN) subtopic aims to support all current and emerging aspects of manufacturing innovations that have the potential to rejuvenate the nation's manufacturing sector and also improve its efficiency, competitiveness, and sustainability. Proposals should be driven by societal/market needs and opportunities, and should identify both the end users of the proposed technology and the proposed pathway to commercialization. Proposals that are responsive to strong societal needs while meeting commercial sustainability thresholds are also encouraged.

The Photonics topic addresses the research and development of new materials, devices, components, and systems that have the potential for revolutionary change in the optics and photonics industries. Proposals should be motivated by market opportunity, a compelling value proposition, clearly identified end users and customers of the proposed technology, and a viable pathway to commercialization.